Wheat has been a staple food in many societies for millennia. People were used to eating a lot of wheat in the form of bread, biscuits, pasta, etc. Some populations, like in many states of north India, had diets based on wheat (in the form of chapatis and rotis) and not much more. Still, until the 1950s people were relatively healthy, with few cases of diabetes, gluten intolerance, and cancer. This changed in the last few decades.
The fact is that the wheat we eat changed radically in the last century. The first modification was an aggressive process of selection and hybridization of the wheat seeds. The plants became much shorter and the grains much bigger. While this resulted in great productivity gains (leading to the so-called green revolution), the resulting grains became very different from what people were eating in the previous centuries. The wheat became very rich in simple starches and the gluten content skyrocketed. At the same time, the content of vitamins and minerals became much lower.
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